Other Name(s):Common Periwinkle, Earlyflowering, Evergreen, Herbe à la Capucine, Herbe de Fidélité, Lesser Periwinkle, Myrtle, Petite Pervenche, Pervenche Mineure, little Periwinkle, Vinca minor, Vincae Minoris Herba, Vincapervinca, Violette des Morts, Violette de Serpent, Violette de Sorcier, Wintergreen.

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Periwinkle is an herb. The parts that grow above the floor are provided to make medicine. Don"t confused periwinkle v Madagascar periwinkle (Catharanthus roseus).

Despite serious safety and security concerns, periwinkle is offered for “brain health” (increasing blood circulation in the brain, supporting brain metabolism, increasing mental productivity, preventing memory and also concentration problems and feebleness, boosting memory and also thinking ability, and preventing early aging of mind cells).

Periwinkle is likewise used for treating diarrhea, vaginal discharge, throat ailments, tonsillitis, chest pain, high blood pressure, sick throat, minister pain and also swelling (inflammation), toothache, and water retention (edema). That is likewise used for promoting wound healing, enhancing the way the immune mechanism defends the body, and for “blood-purification.”

A chemical in periwinkle called vincamine deserve to be converted in the activities to the compound vinpocetine, which is marketed as a dietary supplement.

How does it work?

Periwinkle can lower blood pressure. It deserve to also assist reduce swelling (inflammation) and also have a dry (astringent) effect on the tissues.


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QUESTION beside red peppers, you can obtain the many vitamin C indigenous ________________. Check out Answer
Insufficient proof to Rate performance for...

Preventing mind disorders.Tonsillitis.Sore throat.Intestinal ede (inflammation).Toothache.Chest pain.Wounds.High blood pressure.Other conditions.More evidence is needed to price the efficiency of periwinkle because that these uses.

Natural Medicines considerable Database prices effectiveness based on scientific proof according to the complying with scale: Effective, most likely Effective, probably Effective, perhaps Ineffective, most likely Ineffective, and also Insufficient evidence to rate (detailed description of each of the ratings).


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SLIDESHOW Vitamin D Deficiency: how Much Vitamin D Is Enough? check out Slideshow
Periwinkle is UNSAFE because that anyone to use, but people with particular conditions are especially at threat for harmful side effects.

Pregnancy and also breast-feeding: Periwinkle is UNSAFE. Don"t usage it.

Constipation: Periwinkle has actually a drying result on tissues. This means it have the right to make constipation worse. Don"t usage it.

Low blood pressure: Periwinkle deserve to lower blood pressure. If you currently have short blood pressure, using periwinkle have the right to make it drop as well low. Don"t usage it.

Surgery: Periwinkle deserve to lower blood pressure. There is a problem that it could interfere through blood pressure manage during and also after surgery. Protect against using periwinkle at the very least 2 weeks prior to a scheduled surgery.


Medications for high blood push (Antihypertensive drugs)Interaction Rating: Moderate Be cautious with this combination.Talk through your wellness provider.

Periwinkle seems to to decrease blood pressure. Taking periwinkle along with medications for high blood pressure might reason your blood push to go too low.

Some drugs for high blood pressure encompass captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.


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Report problems to the Food and also Drug Administration

You are encouraged to report an adverse side impacts of prescription medicine to the FDA. Visit the FDA MedWatch website or speak to 1-800-FDA-1088.


Barnett, C. J., Cullinan, G. J., Gerzon, K., Hoying, R. C., Jones, W. E., Newlon, W. M., Poore, G. A., Robison, R. L., Sweeney, M. J., Todd, G. C., Dyke, R. W., and also Nelson, R. L. Structure-activity relationship of dimeric Catharanthus alkaloids. 1. Deacetylvinblastine amide (vindesine) sulfate. J.Med.Chem. 1978;21(1):88-96. See abstract.

Bolcskei, H., Szantay, C., Jr., Mak, M., Balazs, M., and Szantay, C. . Acta Pharm.Hung. 1998;68(2):87-93. View abstract.

Cardinali, G. . Haematologica 1973;53(1):51-64. See abstract.

Chamouni, P., Lenain, P., Buchonnet, G., Merle, V., Bourgain, C., Boyer, A., Girault, C., and also Czernichow, P. Difficulties in the administration of an incomplete form of refractory thrombotic thrombocytopenic purpura, the usefulness the vincristine. Transfus.Sci. 2000;23(2):101-106. Check out abstract.

Csomor, K. And also Karpati, E. Result of vintoperol on platelet aggregation and experimental thrombosis. Arzneimittelforschung. 1994;44(1):36-40. Check out abstract.

Dekoninck, W. J., Jocquet, P., Jacquy, J., and Henriet, M. Comparative examine of the clinical results of vincamine + glycerol matches glycerol + placebo in the acute phase of stroke. Arzneimittelforschung. 1978;28(9):1654-1657. Watch abstract.

El-Sayed, M. And also Verpoorte, R. Methyljasmonate speeds up catabolism that monoterpenoid indole alkaloids in Catharanthus roseus throughout leaf processing. Fitoterapia 2005;76(1):83-90. Check out abstract.

Ena, J., Garcia, A., and also de Mar, Masia M. Vincristine as treatment for idiopathic thrombocytopenic purpura in patients infected with human being immunodeficiency virus. Clin.Infect.Dis. 1996;22(5):880-881. Check out abstract.

Fenaux, P., Quiquandon, I., Caulier, M. T., Simon, M., Walter, M. P., and also Bauters, F. Slow infusions that vinblastine in the treatment of adult idiopathic thrombocytopenic purpura: a report ~ above 43 cases. Blut 1990;60(4):238-241. See abstract.

Filippini, R., Caniato, R., Piovan, A., and Cappelletti, E. M. Manufacturing of anthocyanins by Catharanthus roseus. Fitoterapia 2003;74(1-2):62-67. Check out abstract.

Fischhof, P. K., Moslinger-Gehmayr, R., Herrmann, W. M., Friedmann, A., and Russmann, D. L. Therapeutic efficacy of vincamine in dementia. Neuropsychobiology 1996;34(1):29-35. View abstract.

Gross, Z., Rodriguez, J. J., and Stalnaker, B. L. Vincristine because that refractory autoimmune thrombocytopenic purpura in pregnancy. A instance report. J.Reprod.Med. 1995;40(10):739-742. Watch abstract.

Hirsh, V., Desjardins, P., Needles, B. M., Rigas, J. R., Jahanzeb, M., Nguyen, L., Zembryki, D., and Leopold, L. H. Dental versus intravenous management of vinorelbine together a solitary agent because that the first-line therapy of metastatic nonsmall cabinet lung carcinoma (NSCLC): A randomized step II trial. Am.J.Clin.Oncol. 2007;30(3):245-251. Check out abstract.

Jacquillat, C. And Weil, M. . Sem.Ther. 1964;40(6):395-400. Check out abstract.

Jordan, M. A. And Wilson, L. Microtubules as a target because that anticancer drugs. Nat.Rev.Cancer 2004;4(4):253-265. Watch abstract.

Karpati, E., Biro, K., and Kukorelli, T. . Acta Pharm.Hung. 2002;72(1):25-36. Watch abstract.

Krainer, M., Tomek, S., Elandt, K., Horak, P., Albrecht, W., Eisenmenger, M., Holtl, W., Schramek, P., Stackl, W., Zielinski, C., and also Reibenwein, J. A prospective, open up label, randomized step II psychological of weekly docetaxel versus weekly vinorelbine as very first line chemotherapy in patients with androgen live independence prostate cancer. J.Urol. 2007;177(6):2141-2145. Watch abstract.

Leveque, D. And Jehl, F. Clinical pharmacokinetics of vinorelbine. Clin.Pharmacokinet. 1996;31(3):184-197. View abstract.

Lu, Y., Hou, S. X., and also Chen, T. . Zhongguo Zhong.Yao Za Zhi. 2003;28(11):1006-1009. Check out abstract.

Mans, D. R., da Rocha, A. B., and Schwartsmann, G. Anti-cancer drug discovery and development in Brazil: targeted plant collection as a rational strategy to obtain candidate anti-cancer compounds. Oncologist. 2000;5(3):185-198. View abstract.

Mukhopadhyay, S. And Cordell, G. A. Catharanthus alkaloids. XXXV. Isolation the leurosidine N"b-oxide native Catharanthus roseus. J.Nat.Prod. 1981;44(5):611-613. See abstract.

Mukhopadhyay, S., El-Sayed, A., Handy, G. A., and also Cordell, G. A. Catharanthus alkaloids XXXVII. 16-Epi-Z-isositsirikine, a monomeric indole alkaloid through antineoplastic activity from Catharanthus roseus and also Rhazya stricta. J.Nat.Prod. 1983;46(3):409-413. Check out abstract.

Nakabayashi, M., Ling, J., Xie, W., Regan, M. M., and Oh, W. K. An answer to vinorelbine with or there is no estramustine together second-line chemotherapy in patients v hormone-refractory prostate cancer. Cancer J. 2007;13(2):125-129. See abstract.

Nishii, K., Sakakura, M., Tsukada, T., Ryuu, H., and also Katayama, N. Effective treatment v imatinib an unified with less extensive chemotherapy (vincristine and also dexamethasone) as induction therapy in a very elderly patient with Philadelphia chromosome-positive acute lymphoblastic leukemia. Int.J.Hematol. 2007;85(3):273-274. Check out abstract.

Nomura, T., Maekawa, T., Uchino, H., Miyazaki, T., Miura, Y., Abe, T., Asano, S., Kuriya, S., Nagai, K., Yawata, Y., and . Clinical usefulness of vinca alkaloid sluggish infusion in the treatment of chronic refractory idiopathic thrombocytopenic purpura: a multicenter participating study. Nippon Ketsueki Gakkai Zasshi 1990;53(1):98-104. View abstract.

Papon, N., Bremer, J., Vansiri, A., Andreu, F., Rideau, M., and Creche, J. Cytokinin and ethylene regulate indole alkaloid production at the level of the MEP/terpenoid pathway in Catharanthus roseus suspension cells. Planta Med. 2005;71(6):572-574. See abstract.

Rahmani, R. And Zhou, X. J. Pharmacokinetics and metabolism that vinca alkaloids. Cancer Surv. 1993;17:269-281. View abstract.

Rodriguez-Zapata, L. C. And also Hernandez-Sotomayor, S. M. Evidence of protein-tyrosine kinase activity in Catharanthus roseus roots reinvented by Agrobacterium rhizogenes. Planta 1998;204(1):70-77. Watch abstract.

Rosazza, J. P., Duffel, M. W., el-Marakby, S., and also Ahn, S. H. Management of the Catharanthus alkaloids: native Streptomyces griseus to monoamine oxidase B. J.Nat.Prod. 1992;55(3):269-284. Watch abstract.

Schiavotto, C., Castaman, G., and Rodeghiero, F. Therapy of idiopathic thrombocytopenic purpura (ITP) in patients through refractoriness to or v contraindication for corticosteroids and/or splenectomy v immunosuppressive therapy and danazol. Haematologica 1993;78(6 Suppl 2):29-34. Watch abstract.

Sikorska, A., Slomkowski, M., Marlanka, K., Konopka, L., and Gorski, T. The use of vinca alkaloids in adult patients with refractory chronic idiopathic thrombocytopenia. Clin.Lab Haematol. 2004;26(6):407-411. See abstract.

Ueda, J. Y., Tezuka, Y., Banskota, A. H., Le, Tran Q., Tran, Q. K., Harimaya, Y., Saiki, I., and also Kadota, S. Antiproliferative activity of Vietnamese medicinal plants. Biol.Pharm.Bull. 2002;25(6):753-760. Check out abstract.

van Der, Heijden R., Jacobs, D. I., Snoeijer, W., Hallard, D., and Verpoorte, R. The Catharanthus alkaloids: pharmacognosy and biotechnology. Curr.Med.Chem. 2004;11(5):607-628. Watch abstract.

Vereczkey, L. Pharmacokinetics and also metabolism the vincamine and also related compounds. Eur.J.Drug Metab Pharmacokinet. 1985;10(2):89-103. Check out abstract.

Verma, S., Wong, N. S., Trudeau, M., Joy, A., Mackey, J., Dranitsaris, G., and also Clemons, M. Survival differences observed in metastatic chest cancer patients treated through capecitabine when contrasted with vinorelbine ~ pretreatment through anthracycline and taxane. Am.J.Clin.Oncol. 2007;30(3):297-302. Watch abstract.

Warot, P., Goudemand, M., and Habay, D. . Rev.Neurol.(Paris) 1965;113(4):464-467. Check out abstract.

Waterhouse, D. N., Madden, T. D., Cullis, P. R., Bally, M. B., Mayer, L. D., and also Webb, M. S. Preparation, characterization, and also biological evaluation of liposomal formulations the vincristine. Methods Enzymol. 2005;391:40-57. See abstract.

Wu, M. L., Deng, J. F., Wu, J. C., Fan, F. S., and also Yang, C. F. Significant bone marrow depression induced by an anticancer herb Cantharanthus roseus. J.Toxicol.Clin.Toxicol. 2004;42(5):667-671. See abstract.

Agri Res Svc: Dr. Duke"s phytochemical and ethnobotanical databases. Www.ars-grin.gov/duke (Accessed 3 November 1999).

Carod-Artal FJ. . Rev Neurol 2003;36:860-71. Watch abstract.

Kidd PM. A evaluation of nutrients and botanicals in the integrative management of cognitive dysfunction. Altern Med Rev 1999;4:144-61.. Watch abstract.

Szatmari SZ, Whitehouse PJ. Vinpocetine because that cognitive impairment and dementia. Cochrane Database Syst Rev 2003;1:CD003119.. See abstract.

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The natural Pharmacist. Vinpocetine. Www.tnp.com/substance.asp?ID=573. (Accessed 16 December 1999).